Protein ubiquitylation is a dynamic process that affects the function and stability of proteins and controls essential cellular processes ranging from cell proliferation to cell death.This process is regulated through the balanced action of E3 ubiquitin ligases and deubiquitylating enzymes (DUB) which conjugate ubiquitins to, and remove them from t
Abstract Background Colorectal cancer is the 4th common cancer in China.Most colorectal cancers are due to modifiable lifestyle factors, but few studies have provided a systematic evidence-based assessment of the burden of colorectal cancer incidence and mortality attributable to the known risk factors in China.Methods We estimated the here populat
The P300 paradigm is one of the most promising techniques for its robustness and reliability in Brain-Computer Interface (BCI) applications, but it is not exempt from shortcomings.The present work studied single-trial classification effectiveness in distinguishing between target and non-target responses considering two conditions of visual stimulat